By Julio Gutierrez Alvarado, MD, Contributor to Vein News and www.VeinsVeinsVeins.com
Orhan Rodoplu have published a study investigsting the role of a rotational thrombectomy device for the pharmaco-mechanical thrombolysis for symptomatic acute ilio-femoral deep vein thrombosis.
The study is published in Phlebolgy, volue 36 (full reference below).
Where was the study done ?
Department of Cardiovascular Surgery, Istanbul University Cerrahpasa, Institute of Cardiology, Istanbul, Turkey; Cardiovascular Surgery Clinic, Bagcilar Education and Research Hospital, Istanbul, Turkey; Department of Cardiovascular Surgery, Istanbul Medipol University Medical Faculty, Istanbul, Turkey; Cardiovascular Surgery Clinic, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey; Department of Cardiology, Near East University, North Nicosia, North Cyprus; Cardiovascular Surgery Clinic, Kadikoy Medicana Hospital, Istanbul, Turkey.
- Whar was the study method ?
Retrospective analysis for 82 patients treated between 2013 and 2018.
What are the study Population ?
82 patients with acute deep vein thrombosis comprising the iliofemoral segment whom underwent Pharmaco-mechanical thrombolysis were evaluated.
What device/technique was used in this study ?
The Cleaner thrombectomy device was used.
What was measured and what assessements were made for this study ?
The resolution of thrombi was examined and graded. Development of post-thrombotic syndrome was assessed with Villalta scores.
What are the results of this study ?
75 patients (91.4%) had complete thrombus resolution.
Between 50-99% resolution was noted in 6 patients (7.4%) and in one (1.2%) case less than 50% thrombus resolution was obtained.
Seventy-five patients (91%) of the cohort could be treated in a single session; 7 patients (8.6%) required reintervention.
Improved post-thrombotic syndrome rates were lower at the short term, Villalta scores gradually increased during follow up.
What are the conclusions of this study ?
Pharmaco-mechanical thrombolysis with the Cleaner thrombectomy device is a safe and beneficial method for the treatment of acute iliofemoral deep vein thrombosis. The authors concluded thst long term follow up data of large volume multicenter studies are warranted.
Reference: Rodoplu O, Yildiz CE, Ostaz OM, Beyaz MO, Ulukan MO, Unai O, Conkdayir C, Ugurlucan M. The efficacy of rotational pharmaco-mechanical thrombectomy in patients with with acute iliofemoral deep vein thrombosis: Is the standard of deep vein thrombosis changing ? Phlebology 2021; 36: 119-126.