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Sodium Tetradecyl Sulfate (STS) : A Review of Clinical Uses


Sodium Tetradecyl Sulfate (STS) : A Review of Clinical Uses


An article published by Jenkinson HAWilmas KMSilapunt S from the Department of Dermatology, University of Texas McGovern Medical School at Houston, Houston, Texas in Dermatologic Surgery, April 2017 reviews the clinical use for sodium tetradecyl sulfate (STS). 


The authors summarize the use for sodium tetradecyl sulfate: 


Varicose veins



pyogenic granuloma

cherry angioma

Kaposi sarcoma

lymphangioma circumscriptum

digital mucous cyst

ganglion cyst


angiokeratoma of Fordyce

pseudocyst of the auricle

verruca. C


The authors report "commonly reported side effects" include:






telangiectatic matting



Serious side effects such as anaphylaxis, pulmonary embolism, stroke, and myocardial infarction have also been reported. Most sources were case reports and small prospective studies, as such the strength of data supporting many uses is limited by small sample sizes and lack of controls.

Dr Karamanoukian's note: This is a general review for use of STS in dermatology. We use it inour office for varicose veins and telangiectasias and have had good results. 
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