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Recanalization Rates After Endovenous Ablation with GLUE

 

Division of Vascular & Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, South Wing, 14th Floor K Block, Pokfulam Road, Hong Kong, Hong Kong. Electronic address: ycchan88@hkucc.hku.hk.
Division of Vascular & Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, South Wing, 14th Floor K Block, Pokfulam Road, Hong Kong, Hong Kong.
Hong Kong
Researchers have published an article which investigated the use of cyanoacrylate glue in closing incompetent great saphenous veins in the treatment of venous insufficiency. The study was published in Journal of Interventional Radiology, March 8, 2017.
Follw-up was done by serial clinical and duplex examinations was performed at 1 week, 1 month, 6 months, 12 months, and 24 months of 108 legs in 55 patients.
Of 108 legs, 2 had minimal extension of thrombus to deep vein, and 4 had superficial thrombophlebitis.
Great saphenous vein closure rates were 97.2%, 92.3%, 89.2%, and 75.7% at 1 week, 1 month, 6 months, and 12 months after the procedure.
The authors concluded some limitations with the study:  Despite 97.2% closure rates at 1 week, recanalization was observed in GSVs with larger diameter.
Other notable conclusions:  The use of endovenous cyanoacrylate to treat varicose veins caused by incompetent GSV was safe. GSVs < 6.6 mm in diameter had a closure rate of 90.0% at 12 months. 
Dr Karamanoukian's comment: At 12 months, the nearly 25% recanalization rate is a limiting factor in advocating its cyanoacrylate glue in treating venous insufficiency of the great saphenous vein. 


Hratch L Karamanoukian MD FACS RVT RPVI RPhS

Article purchase here from the Journal of Vascular and Interventional Radiology (JVIR) 
http://www.jvir.org/article/S1051-0443(17)30152-5/fulltext?rss=yes


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